2-Chloro-quinoline-5-carboxylic acid

2-Chloro-quinoline-5-carboxylic acid - Names and Identifiers

Name	2-Chloro-5-quinolinecarboxylic acid
Synonyms	2-Chloroquine-5-methane acid 2-Chloroquinoline-5-carboxylic acid 2-Chloro-5-quinolinecarboxylic acid 2-Chloro-quinoline-5-carboxylic acid 5-Quinolinecarboxylic acid, 2-chloro-
CAS	1092287-30-3
InChI	InChI=1S/C10H6ClNO2/c11-9-5-4-6-7(10(13)14)2-1-3-8(6)12-9/h1-5H,(H,13,14)

2-Chloro-quinoline-5-carboxylic acid - Physico-chemical Properties

Molecular Formula	C10H6ClNO2
Molar Mass	207.61
Density	1.496
Boling Point	411.9±25.0 °C(Predicted)
pKa	2.28±0.10(Predicted)
Storage Condition	Inert atmosphere,Room Temperature
Sensitive	Irritant
MDL	MFCD11226761

2-Chloro-quinoline-5-carboxylic acid - Introduction

2-Chloroquinoline-5-carboxylic acid, also known as, acid, is an organic compound. The following is a description of its nature, use, preparation and safety information:

Nature:
2-Chloroquinoline-5-carboxylic acid is a white solid with a special chemical structure. Its chemical formula is C10H6ClNO2 and its molecular weight is 215.61. Its melting point is about 180-185°C.

Use:
2-chloroquinoline-5-carboxylic acid has important applications in the field of medicine. It is one of the precursor compounds of the anti-malaria drug malaria. It also has potential anticancer and antiviral activities and has been used as a reagent and ligand in related studies.

Preparation Method:
There are many methods for preparing 2-chloroquinoline-5-carboxylic acid, the common ones include:

1.2-chloroquinoline -5-carboxylic acid is generated by acidic hydrolysis of 2-chloroquinoline;
2. 2-Chloroquinoline-5-carboxylic acid is synthesized by reaction steps such as oxidation and carboxylation of 2-chloroquinoline.

Safety Information:
2-chloroquinoline -5-carboxylic acid in the use and handling process should pay attention to safety measures. It may cause irritation and damage to the human body, so direct contact with the skin, eyes and respiratory tract should be avoided. Personal protective equipment, such as laboratory gloves, goggles and protective masks, should be worn during operation. In addition, the compound should be stored and handled properly to avoid adverse reactions or accidents with other chemicals. In the event of an accident, seek medical attention immediately and provide relevant chemical composition information.

Last Update：2024-04-09 20:52:54